Crash when instantiating QApplication subclass within main()

import sys
from PySide2 import QtWidgets

class AppSubclass(QtWidgets.QApplication):
    def __init__(self, *args, **kwargs):
        super().__init__(*args, **kwargs)

def main():
    app = AppSubclass(sys.argv)

main()
# Seg fault 11 under macOS 10.14.6

import sys
from PySide2 import QtWidgets

class AppSubclass(QtWidgets.QApplication):
    def __init__(self, *args, **kwargs):
        super().__init__(*args, **kwargs)

app = AppSubclass(sys.argv)
# No crash

Process:               Python [63981]
Path:                  /Users/USER/*/Python.framework/Versions/3.10/Resources/Python.app/Contents/MacOS/Python
Identifier:            org.python.python
Version:               3.10.2 (3.10.2)
Code Type:             X86-64 (Native)
Parent Process:        bash [7079]
Responsible:           Python [63981]
User ID:               501

Date/Time:             2022-02-03 23:09:04.556 +1000
OS Version:            Mac OS X 10.14.6 (18G9323)
Report Version:        12
Anonymous UUID:        DA5A69F6-6D98-A47D-DFF6-80B091D3DBF3

Sleep/Wake UUID:       125DE0E6-768C-4225-A5C7-9338DA7FE41B

Time Awake Since Boot: 17000 seconds
Time Since Wake:       13000 seconds

System Integrity Protection: enabled

Crashed Thread:        0  Dispatch queue: com.apple.main-thread

Exception Type:        EXC_BAD_ACCESS (SIGSEGV)
Exception Codes:       KERN_INVALID_ADDRESS at 0x0000000000000000
Exception Note:        EXC_CORPSE_NOTIFY

Termination Signal:    Segmentation fault: 11
Termination Reason:    Namespace SIGNAL, Code 0xb
Terminating Process:   exc handler [63981]

VM Regions Near 0:
--> 
    __TEXT                 0000000107d7e000-0000000107d7f000 [    4K] r-x/rwx SM=COW  /Users/USER/*/Python.framework/Versions/3.10/Resources/Python.app/Contents/MacOS/Python

Thread 0 Crashed:: Dispatch queue: com.apple.main-thread
0   org.python.python             	0x0000000107f38f65 PyObject_GC_UnTrack + 21
1   org.python.python             	0x0000000107e30e1e subtype_dealloc + 174
2   org.python.python             	0x0000000107e094ce insertdict + 1086
3   libshiboken2.abi3.5.15.dylib  	0x000000010871cc2e MakeQAppWrapper + 158
4   libpyside2.abi3.5.15.dylib    	0x00000001093029a4 PySide::destroyQCoreApplication() + 148
5   libpyside2.abi3.5.15.dylib    	0x00000001093028ed PySide::runCleanupFunctions() + 141
6   QtCore.abi3.so                	0x000000010b464ea1 SbkQtCoreModule___moduleShutdown(_object*) + 33
7   org.python.python             	0x0000000107e1ae4b cfunction_vectorcall_NOARGS + 267
8   org.python.python             	0x0000000107f714a3 atexit_callfuncs + 147
9   org.python.python             	0x0000000107f0f2f2 Py_FinalizeEx + 66
10  org.python.python             	0x0000000107f37259 Py_RunMain + 2905
11  org.python.python             	0x0000000107f3752b pymain_main + 411
12  org.python.python             	0x0000000107f3758b Py_BytesMain + 43
13  libdyld.dylib                 	0x00007fff6cc163d5 start + 1

Thread 1:
0   libsystem_pthread.dylib       	0x00007fff6ce093f0 start_wqthread + 0

Thread 2:
0   libsystem_pthread.dylib       	0x00007fff6ce093f0 start_wqthread + 0

Thread 3:
0   libsystem_pthread.dylib       	0x00007fff6ce093f0 start_wqthread + 0

Thread 4:
0   libsystem_pthread.dylib       	0x00007fff6ce093f0 start_wqthread + 0

Thread 0 crashed with X86 Thread State (64-bit):
  rax: 0x000000010ba523e0  rbx: 0x000000000000009c  rcx: 0x0000000000000000  rdx: 0x0000000000000200
  rdi: 0x0000000108303b40  rsi: 0x000000010b8d55b0  rbp: 0x00007ffee7e81340  rsp: 0x00007ffee7e81340
   r8: 0x0000000000000000   r9: 0x27bda66b60f8266d  r10: 0x00007ff72981b000  r11: 0x00007ff72981b228
  r12: 0x0000000108303b40  r13: 0x0000000108216fc0  r14: 0x0000000108303b40  r15: 0x00007ff72a936010
  rip: 0x0000000107f38f65  rfl: 0x0000000000010246  cr2: 0x0000000000000000
  
Logical CPU:     0
Error Code:      0x00000006
Trap Number:     14