(pyside) $ pip install pyside6-essentials
Collecting pyside6-essentials
  Using cached PySide6_Essentials-6.7.1-cp39-abi3-macosx_11_0_universal2.whl.metadata (3.7 kB)
Collecting shiboken6==6.7.1 (from pyside6-essentials)
  Using cached shiboken6-6.7.1-cp39-abi3-macosx_11_0_universal2.whl.metadata (2.5 kB)
Using cached PySide6_Essentials-6.7.1-cp39-abi3-macosx_11_0_universal2.whl (153.9 MB)
Using cached shiboken6-6.7.1-cp39-abi3-macosx_11_0_universal2.whl (386 kB)
Installing collected packages: shiboken6, pyside6-essentials
Successfully installed pyside6-essentials-6.7.1 shiboken6-6.7.1 

(pyside) $ pyside6-designer
Unable to find Python library directory. Use a framework build of Python. 

(pyside) $ python -c "import sys; print('Framework build:', hasattr(sys, '_framework'))"
Framework build: True 

(pyside) $ which python
/opt/homebrew/Caskroom/miniforge/base/envs/pyside/bin/python