Purify does not support programs that are incrementally built or with fixed positioning. Qt is built with both of these flags by default. It is necessary to go into mkspecs/yourqmakespec/qmake.conf and set the LFLAGS to /INCREMENTAL:no /FIXED:no to solve this problem. It would be useful if configure had an option for Purify, in the same manner that there is one for Boundschecker.