The issue is that the wheel / package contains a file called "libclang.so.6.0" whereas the executable expects a file called "libclang.so.6" as seen by running:

$ readelf -d ~/.virtualenvs/py3_qt511_official_clang/lib/python3.6/site-packages/PySide2/shiboken2

 0x0000000000000001 (NEEDED)             Shared library: [libclang.so.6]

Trying to execute the file gives:

/home/alex/.virtualenvs/py3_qt511_official_clang/lib/python3.6/site-packages/PySide2/shiboken2: error while loading shared libraries: libclang.so.6: cannot open shared object file: No such file or directory

I have this fixed in my upcoming changes for PYSIDE-749.
So far there have been no bug reports about this (nobody using shiboken on Linux?).
Question is if we plan to release 5.11.1, should we fix it there as well.